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@markymarkfl

@dalegantous , Did you get any measurements of tumor size and CA19-9 before, during, and after treatment with the durvalumab and oleclumab, or an assessment by the trial research team of how effective it was?

Did you have specific mutations or other unique circumstances to enter that trial?

Best wishes on your journey with Folfirinox!

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Replies to "@dalegantous , Did you get any measurements of tumor size and CA19-9 before, during, and after..."

Tumor did not shrink after immunotherapy, however surgery was only a few weeks after the infusions. Tumor size on CT scans was 2.9 cm but at surgery it measured 3.5 cm. Don't know if this was due to tumor growth or just accuracy of CT scans. I've also read about the possibility of pseudoprogression, where the tumor appears to grow after immunotherapy but is not actually growing due to the cancer, but swelling due to the immunotherapy. I have no idea whether that actually applies in my case. CA 19-9 dropped from 165 before infusions to 145 at time of surgery.
Cheers,
Dale