Yes, your description - minus Depakote and substituting weight gain for weight loss -aligns with my long history of what was eventually diagnosed as Idiopathic Intercranial Hypertension. IIH led to a cerebrospinal fluid leak and surgical implantation of a ventriculoperitoneal shunt. IIH has become better known because of its association with the Mirena IUD (I do/did not have one) and the lawsuit against Bayer Corp. - and that raises the question for many women as to whether hormone therapy may be contributing to IIH and related symptoms. Another aspect to investigate might be mast cell activation and dysautonomia.

I have also taken Depakote but only on an as needed basis for quick relief of auras. My auras are infrequent. They may occur on a one a year or two year period with no head pain. I have suffered for years with head pressure similar in some ways to yours. Over decades I have found no relief from any medication and after all testing have not determined why. Your post caught my attention because I am sensitive to many medications, Depakote being the last. I find it difficult to describe the effect except that I feel crappy all day after taking just one. The only med that stopped auras was Rizatriptan and that was stopped for fear of causing a stroke. Sorry If I haven't been much help but it seems that at 78 it has become worse with age.
ps FYI for anyone else. Years ago before auras I had severe pain headaches for decades. After Radio Frequency Ablation the severe pain headaches ceased and severe head pressure appeared.