Hi Colleen,
I had germline testing (which tests for hereditary gene mutations) done through the Promise Study. It is free for prostate cancer patients. Patients can apply through their website and complete the sample collection at home. The results can identify if some of the powerful new immunology therapies might be effective.

I have localized Gleason 9 prostate cancer with current PSA < .03 following 2 years of ADT + abiraterone and prednisone as well as proton therapy. Rather than do somatic testing (genetic testing of prostate cancer tissue or circulating DNA) on the original biopsy samples, my oncologist wants to wait and test if/when there is a biological recurrance evidenced by a rise in PSA. The reason to wait is because the tumor genetics can change from the original biopsy through modification or mutation.