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Hi there! My doctor advised splitting the Methotrexate dose 12 hours apart to hopefully help avoid or lessen nausea. He didn't tell me to avoid folate on dosage days, but I read this on my own and have not taken it those two days. I took 30 mg the day before, and this week my nausea was less and only lasted a day. It was lasting a week previously.
I feel like maybe the dr doesn't read the latest research and is using old protocol. I'm not going to disclose to him that I'm experimenting on my self. He was critical of me using CBD oil for pain, stating one study said it might harm the liver. I thought this was rich, considering he was prescribing a well-known liver damaging drug. 😬
That is a shame that you had to stop taking what was working. I think I read that injections would bypass the liver. Was that a suggestion?
Replies to "Hi there! My doctor advised splitting the Methotrexate dose 12 hours apart to hopefully help avoid..."
They bypass the GI absorption which is directly processed by the liver. I was able to stay on the drug much longer after I went with weekly injections.
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@jdnc2023 no, the injection was not suggested. I live in Ontario, Canada, and because we are on the government health plan the government decides what they are willing to pay. I have been approved for two injections - first Stelara and then Skyrizi, and both did nothing for me. Then my dermatologist applied for me to receive injerejected for two other injections and I didn’t “qualify” for either. Now I have been approved for Bimzelx and although it is working, I don’t know how it will affect my liver in the long run. Dermatologist says not to worry. 🤷🏼♀️