@krisrwalters You might want to talk more about tamoxifen with your oncologist. For us post-menopause, tamoxifen only blocks estrogen in the breast, but has estrogen-like effect in most of the rest of the body including bone, heart, skin, and brain. I do not believe it damages collagen.
I have been amazed at the estrogen effect I’ve seen in my body: a reverse of GSM (vaginal atrophy, dryness, etc), and better skin elasticity. It seems to be dose dependent. At 20 mg I had better estrogen like affects - but also came with moodiness and headaches. I did not have hot flashes, but it did seem to take longer for my body to cool off if I got overheated in a hot car, or after hike in the sun. At 5 mg, I still had good GSM response, less moodiness. The jury is still out on whether the headache I now have after 3 months on this dose is actually from tamoxifen or other causes. At closer to 2.5 mg, I lost the benefit of the estrogen-like boost and again had moderate GSM. (Yep, I’ve tried them all working through which dose is best, with a drug holiday between 20 mg and 5 mg).

Here is a case of someone with hypermobile Ehler Danlos. I realize there are different forms of the condition, so this may not apply to you. My cousin has Ehlers Danlos and had major major multiple surgeries to his legs and knees at a young age.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514306/
Wishing you the best!