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Frustrated by zero results

Autoimmune Diseases | Last Active: Apr 6 1:11pm | Replies (33)

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Yes. I was prescribed folate 1 mg daily. I did some extra googling and decided to take some folinic acid 10mg the day before and the day after the methotrexate to see what happens. It's supposed to be more potent. This is my first week trying it. I split the MTX dose into 3 Wednesday night and 3 Thursday morning. I was pretty nauseated this morning, but hopefully better soon.

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Replies to "Yes. I was prescribed folate 1 mg daily. I did some extra googling and decided to..."

@jdnc2023 As far as I know you cannot take Methotrexate and Folic Acid on the same day - and the Methotrexate dosage should not be split. If you are doing that, it could be the reason for your nausea … perhaps …?

At any rate, let your rheumatologist know that you have been tweaking your dosages, and also that you have been taking folinic acid as well. Changes and additions you make could prevent the Methotrexate from working as it probably should or could, perhaps …

I was on Methotrexate for psoriasis and it worked great, although it was about six months before I saw results. It was the only medication that worked for me finally but I had to go off it after three or four years on it, because I have fatty liver disease and apparently it is not good for me to be on this drug long term because it could affect my liver.

But you are so right about medications just creating other side effects while having no effect on the condition for which they are prescribed! Been there, with other meds!