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Tamoxifen and anastrozole

Breast Cancer | Last Active: Apr 10 11:36pm | Replies (72)

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@traci999

I had a partial mastectomy in September 2023. Surgery went well. finished 4 weeks of radiation and I did well thru that too. Then time for Anastrozole....started with headaches which did eventually subside. The mood swings, severe exhaustion, sleepless nights and joint pain are horrible. My dr is working with me to get me on meds to try to soften the affect but to be honest I don't know if you can counteract these side effects. I am now on two-week rest from the medication just to see if it's the meds causing these results, but I am sure it is. Please if anyone can give me any suggestions, I'm up for them. Good luck to you all on your journey....

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Replies to "I had a partial mastectomy in September 2023. Surgery went well. finished 4 weeks of radiation..."

I'm sorry to hear you are having such difficulty with anastrazole. My oncologist suggested to take it with tart cherry juice when I started taking anastrazole. It seems to help. Try it, it may help you.

It's strange how I was on Anastrozole for 90 days. Oncology nurse and my surgeon were surprised that I had no side effects and yet the shrinkage of tumor was great. Then I renewed my prescription. In about 2 weeks my side effects (fatigue, bone ache, flu like symptoms - it was NOT the flu), depression, carpal tunnel syndrome, (my crochet wrist got 10x worse), loss of interest of EVERYTHING. So, why was the first 90 days fine? I switched to renewed prescription and I fell apart. I looked up manufacturers of Anastrozole and there are quite a few!! I know, you'll be told . . . "It's the same." Yeah, like levothyroxine and Synthroid are the same!! NOT. And that fact has now surfaced after all these years, that there is something to that. In talking about Synthroid vs. Leve, they discussed the carrier of the drug - the extras in the formula considered benign. Levo - after 2 wks did nothing. My Dr. at the time switched me to Synthroid immediately. Within 4 days I felt reborn. SOOO, I wish I knew the manufacturer of the first batch of Anastrozole. I think it behooves me to dig into that with the pharmacy. Some formulas work well, and some don't!