I wonder if Tymlos and Forteo only help trabecular bones.

I started with full dose Evenity and then for the next two months, declined the second shot and only had one, so a half dose. I'll let you know my results. But most people do fine with it of course.

I continued to have side effects with Tymlos. I just want to make sure I am clear that ramping up/partial dose made it possible but did not entirely get rid of side effects.

I absolutely could not tolerate Forteo. This was before Tymlos was available. I tried everything. I went to an immunologist. I even used my kid's insulin syringe to draw up a 10% dose which was just not tolerable. So I get it when you say you couldn't tolerate it.

With Tymlos, I used a blood pressure cuff, hydrated, ate salty things, played around with timing, and after all my fractures (7 spinal) was grateful to tolerate 7 clicks for much of the time. Mysteriously I never tolerated 8!

We are all different. I am having neuro issues and joint pain on Evenity but the thing is, with Evenity, there is quite substantial bone growth (if it is working) in just a few months.

I hope you find a path to better bone health and I get it!

@sallyj2 just want to repeat: Tymlos does not apparently cause loss of cortical bone, as Forteo might- according to my docs.

And I had 9% gain in hip on Tymlos.

ps this is not to say Forteo isn't a good medicine!

I am so happy you had a gain in your hips! My doctor said that he thought eventually, by the end of treatment, that people would see gains in their hips, but that it was theoretically possible to lose a little cortical bone at first. He said, that might not correlate to increased fracture risk. Hard dilemmas!

Yes it's interesting that docs say fracture risk improves even if bone markers don't show what we had hoped!

We are all between a rock and hard place and doing the best we can. I am looking up hip pads on Amazon! My femur neck is never going to be good enough, no matter what I do for meds or how long.

I read there are ppl wearing special protective shoes while healing foot fractures, can't remember what source. Maybe look into that also?

I think this msg meant for @beanieone

Thanks @beanieone. I'm sorry that I responded to @mayblin by mistake. I wondered why you quit Tymlos after 9 months? I'm so glad you got good and excellent results. I did check Evenity's website. It is wonderful but also frustrating that the people that post on this website seem to know more about osteoporosis than my doctors.

Thanks @maybin. I will check that out.

Hi @drsuefowler, Thanks for your support.

I quit Tymlos after nine months; the last five were pretty debilitating. My doc knew about each new issue and I ended up telling him the cure was worse than any fracture I could or have suffered. Doc said no medical info about my symptoms.

Switched to Evenity and breathed a sigh of relief. I phoned Radius and made a long statement about symptoms and noted that several now appear on their website. Felt like a pioneer! 😆 Cheers!

I was disappointed w/Tymlos results - my doctor was too. Unfortunately, they had no helpful insights or answers. Spine improved slightly; hip not at all. Still osteoporosis on the DXA. Doc now mentions prolia - doesn't mention any concerns like the difficulty of stopping after starting, (which I only learned about here). Concerning for women in their '50s. We could be on it for 3-4 decades!

I know my post probably isn't as helpful - others are chiming in with better info. Just think it's important to realize that some of us may not get the results often touted here or by our docs. We can do everything right - meds, diet, weight training, zero smoking or booze and still have issues. I feel like some docs oversell us on the effectiveness?