@pattier I too had DCIS but to simplify things I just call it cancer. Fact is, some DCIS recurs more often than true cancer that has been appropriately treated. And there is a 50% chance of a recurrence being invasive not just another DCIS. So the fear is there, and the need to get treatment.

I had grade 2 like yours. Depending on why it is scored a 2 makes it more concerning to me. I do not know the breakdown of my score. But if the miotic (rate of growth) is high, along with some solid type cancer cells (vs cribriform or papilloma) there might be a greater chance of it breaking out of the duct.

Pathology looks at whether the myoepithelial cells surround the lesion - if it does it’s good and indicates the cancer cells have not broken through the duct. Pathology also considers whether there is abnormal p53 immunohistochemical expression. If normal p53 is present then it is another indication that the DCIS is contained.

For some of us, removing the DCIS and treatment means we’re done. For others, there may be a recurrence. And although there are indicators, like p53 and the myoepithelial layer - they still can’t predict 100% accurately of who will have a recurrence. And that’s why I just call my DCIS cancer - because the potential of cancer is very real. And the difference between DCIS vs cancer takes more explanation than some friends want to hear.

I try to be very respectful and aware, though, when talking or posting about my experience. Because I haven’t faced the same risks and chemotherapy that others with invasive cancer have. I always hope that I express empathy and not make treatment sound easy, because I have not experienced some of the situations, treatment, risks, that others have.