Yes I take an antibiotic when I have a flare up. Vertex , the pharmaceutical that produces Trikafta and my CF docs are seeing if they can appeal the denials. If I understand it correctly treatment for a CFTR related disorder differs from CF treatment which differs from bronchiectasis. But all three involve bronchiectasis. I may end up waiting a few years for more research into whether modulators such as trikafta are clinically trialed on my type of symptoms and my severely pathogenic p.phe508DEL variant and second variant since results say I'm for sure a carrier. I do not live in a state that has a good CF center or good pulmonologists.