@richardfrancine Hey there, I'm sorry about your migraine troubles. It's exhausting trying so many different meds and inevitably discouraging when they don't work . Managing migraines is like other chronic conditions, very much trial and error and possibly a crap shoot. Everyone responds differently to different treatments but I can say that I have tried Vyepti medication in addition to all the others you mentioned and like you did not receive much help. I even tried a powdered abortive medication to be taken upon an onset. In all honesty I think any relief I ever received was placebo but again that's me some things do work for people.

Do you mind sharing a little bit more about your journey with migraine headaches? Outside of medication treatments, may I ask what sort of lifestyle changes you have implemented or changed, such as stress management or diet?