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Started Repatha - Side Effects

Heart & Blood Health | Last Active: 3 days ago | Replies (62)

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@agb

I'm approaching 6 months on Repatha with no side effects.

I saw something about the trials but have not seen enough on it to have an opinion.

Here's another way to look at this: we're all test subjects right now and it will take many years to know the long term effects from these new drugs. Around 20+ years ago, I was in the original niacin trial. Niacin raises HDL and lowers LDL; has to be good, right? We took 3000 mg daily of Niaspan, and after the trial, I took this for years. Just a few years ago, my doctor abruptly stopped me from taking it as it's now known that the long term effects are an increase in cardiovascular events, even though the HDL and LDL numbers looked better. Something else was going on.

Repatha has lowered my LDL to 27 (from 109) and my Lipoprotein B from 125 to 40, so short term, looks good. I'm hoping my taking this helps my kids, as they both have the inherited high cholesterol gene, and medicine will learn more as we go forward.

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Replies to "I'm approaching 6 months on Repatha with no side effects. I saw something about the trials..."

3+ months on Pushtronix Repatha. No noticeable side effects. LDL down to 9, APOb 16, Trig 36, HDL 55, Lp(a) < 8. Hoping it will help my advanced CAD. Used Niacin 3g per day for many yrs based on Mayo prescription. No measurable effect on CAD.

Thank you for such a thought out response. You are right. After my hysterectomy over 30 years ago my doctor insisted that I take hormone replacement. He said it would be “good” for me. Then years later he said to get off of it right away due to the breast cancer revelation. I’ve been on Effexor for over 10 years only to recently find out it caused my rapid bone loss. After my second dose of Repatha I had strong side effects the next day (yesterday) today they aren’t as severe. I hope that’s a sign that it won’t keep being bad. i'm 76 i don't want to spend my last years feeling bad just to add a couple of years to my life, if it even will add a couple of years.

You are right, we are lab rats. I also don’t have side effects from Repatha, but it makes you wonder what terrible effect they will find out occurs with long term use. And, like other meds, will it reduce numbers but create more cardiac events. I think it is more about profit than health, BUT, that said, I am on it and my numbers are good. However, I am concerned about long term effects. Hopefully I will have died a peaceful active old age death by then.

I agree about being test subjects. I’m just going for quality, not quantity of life. Many people can take these drugs without a problem, but I can’t. I’m bearing down on organic fresh diet, exercise (8,000-12,000 steps a day and yoga), sleep, and keeping my weight at a normal level. I also do sleep meditations. Trying to stay away from drugs as much as possible. Time will tell.