I'm 20 months post Iovera and TKR. Had a normal recovery with just the kneecap numbness until 2 months ago when I experienced the same vice like pain at the knee that shot down the outside of my lower leg into my foot. Horrible pain and locked up leg for 15 min or so, then it slowly subsides. It happens regularly now. Dr says most likely a nerve issue. I'm getting an MRI today. You seem to be the only one here with a very similar experience so not sure if this Iovera related or not.