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Share results of PRP knee injection therapy.

Bones, Joints & Muscles | Last Active: Apr 4 8:12am | Replies (45)

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@topper

I have had hyaluronic injections in both knees since about 2007. I have gotten them annually until this year when I needed them after 6 months. There are a variety of hyaluronic injections. I get the ones medicare approves. The doctor giving them to me uses a spray first that eliminates the pain of needle entry and minimizes the pain of the gel going in. It takes a couple weeks for them to be effective. Also, my orthopedic surgen said that although cortisone shots help temporarily, they are more harmful in the long term. Can some one from Mayo Clinic comment on this, please.

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Replies to "I have had hyaluronic injections in both knees since about 2007. I have gotten them annually..."

Studies seem inconclusive: if it helps you, great!

"Hyaluronic acid has been FDA-approved to treat osteoarthritis of the knee via intra-articular injection. A 2012 review showed that the quality of studies supporting this use was mostly poor, with a general absence of significant benefits, and that intra-articular injection of HA could possibly cause adverse effects. A 2020 meta-analysis found that intra-articular injection of high molecular weight HA improved both pain and function in people with knee osteoarthritis.