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CA 19-9, sensitivity and responsiveness to treatment

Pancreatic Cancer | Last Active: May 28 5:18pm | Replies (17)

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@markymarkfl

Sitting in the chemo chair getting GAC #30 as I type. Just got my CA19-9 result a few minutes ago. All the data I have from one lab is in the attached graph.

Data in short:
-- GAC worked better for me than Folfirinox.
-- Reducing Abraxane aligned with increasing CA19-9.
-- Missing a treatment aligned with increasing CA19-9.
-- Restoring full Abraxane aligned with two small decreases in CA19-9.
-- Reductions of CA19-9 after missed Tx (131 -> 129 -> 122) not as sharp as last time at similar levels (158-> 105).
-- Upward slope after missed Tx not quite as steep as slope between recurrence suspected & confirmed.
-- CA19-9 will rise and tumors will grow quickly when off treatment.
---- Warrants consideration if washout period is required before a clinical trial.

Perception:
The slower response to full doses after missed Tx _seems_ to suggest some resistance is developing, or at least less control with current dose. Aligns w/ tumor growth shown on recent scans after the missed Tx.

Click on graph to enlarge.

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Replies to "Sitting in the chemo chair getting GAC #30 as I type. Just got my CA19-9 result..."

@markymarkfl Thanks for sharing your CA 19.9 graph! You prompt me to update and enhance a similar but less sophisticated graph my son generated for me a few months ago. It's important, given CA19.9 levels' significance as a determinant/indicator for diagnosis, treatment and patient care planning.
And thank you again for generously giving your valuable time to help so many others fight this nasty disease.