Hi jaguarqueen - Thanks for the complement. From what I understand from the main Evenity study, it's not necessarily that Evenity increases a chance of heart issues, but that it might be more about the protective response to alendronate. While this might be dated information, you can watch Dr. John Bilezikian discuss this point here https://youtu.be/xJoB_xLZeMs?si=HRUIoZhynJcFPQfc&t=6133 . If you rewind a bit from here, he talks about other adverse effects. If you rewind more, he talks about Tymlos as well.

That said, both drugs are highly effective. The one standout is the performance on hip / femur areas. Evenity excels here. I also know Evenity does well after alendronate, where Tymlos / Forteo struggle a bit, especially in the hip / femur. Attached is a backup slide from my presentation on medications showing the performance of Evenity following bisphosphonates (which would include alendronate).

I personally chose Evenity over Tymlos for two reasons. The performance, especially for the hip / femur area, and because PTH drugs like Tymlos could raise urine calcium. That's not good if you are hypercaliuric, like I am.

Hopefully that helps a bit. Tough decision for sure. I wish you the best of luck.