ncbi/nlm/nih.gov/pmc/articles/PMC7973401

Please let me have your thoughts.

I did see an Endo at a major teaching hospital. Recommendation was to remain on Prolia as long as possible (subject to periodic testing), then go Reclast, ultimately going back to Prolia. This made sense to me. FYI - I am 81+ years old, but otherwise reasonable healthy. I went to the hospital since I was unable to understand how a 12% drop could occur.

I then located a local (within 50 miles) Endo (with a specialty in osteoporosis) to treat me and monitor my progress. He impressed me with his thoroughness. His course of treatment was to go off Prolia (anytime soon) to Forteo and after 24 months back to Prolia. With my ongoing dental problems it sounded like a miracle. Until my research identified the rebound problem.

I have had 2 MRI's, one locally indicating an 12% bmd drop in my hip over a two year period and about the same drop as over past six years. A retest showed a 9% drop. An MRI at the hospital, however, showed an improvement of 3% over nearly the same 6 year period. Since being on Prolia (accordingly to my "local" DexaScan) the BMD of the neck has not changed, while the total hip actually decreased 10%. I JUST TOOK ANOTHER LOOK AT MY DEXASCAN HISTORY AND INCLUDED THIS PARAGRAPH FOR MY BENEFIT. I think I just ratified my decision to stay on Prolia. It does make we wonder if I am already back to my Prolia baseline.