Thank you for your reply. I have been diagnosed with osteoporosis and was on Fosamax for one year and did reasonably well with it and good bone results and then asked my doctor for a drug holiday to see if some unpleasant symptoms were related, GERD was but aches and pains were not. Then a diagnosis of PMR. My doctor definitely recommends I go back on Fosamax. Taking 20mg of prednisone for PMR. I know Fosamax definitely has risks and I don’t like taking anything but I also want to be reasonable. Osteoporosis also has big risks.