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Has anyone tried the medication leflunomide?

Polymyalgia Rheumatica (PMR) | Last Active: 4 days ago | Replies (46)
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@jane2023

Hi, I am wondering what taper schedule you used with your prednisone once the LF started working for you.
I am now 3 months on LF and feel the best I have in 2 years. Now at 5 mg pred, I'm being careful to not create any increased inflammation and set my self back. But I do feel very good and so hopeful. Thanks so much for your information. J

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Replies to "Hi, I am wondering what taper schedule you used with your prednisone once the LF started..."
tjpa444 | @tjpa444 | Apr 13 7:48pm

Hi, I started taking LF a month ago with very good results, i.e., reduced shoulder and hip pain during the night by 40-50% and hand morning stiffness the same. I have been dealing with PMR/RA for over six years. Methotrexate did not help me, along with a few other standard RA medicines. Switched to Prednisone 20mg and tapered off 2-3 times down to 5 mg. Below 7-8 mg symptoms started to get more severe again. My Rheumatologist really wanted me off prednisone so I stopped completely over a year ago and pursued a better nutrition and mostly plant based diet. This approach did help to a degree and I continue it with LF , 20 mg per day. Thanks for this forum and best wishes to you all.

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