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Husband with AML facing a stem cell transplant

Bone Marrow Transplant (BMT) & CAR-T Cell Therapy | Last Active: Sep 7, 2024 | Replies (117)
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@mary612

Good morning Lori!

Again, I am so grateful for your reassuring guidance and suggestions. Makes me feel not so alone in all this.

Your encouragement is gold and just what I need to hear now.

My husband is starting cycle 2 of his induction chemo today! Thankfully this chemo cocktail is well tolerated. He will have another bone marrow biopsy on day 21, April 8. He achieved partial remission with 2% blasts from cycle one. They detected the mutations and chromosome changes in the biopsy so she wants to try to clean that out with this cycle while the transplant team works on finding a donor. We don’t know how long that will take. But we do know the transplant doc thinks my husband is a good candidate for the transplant which is a step in the right direction!

My faith is strong and helps me stay in the present, with hope in my heart for coming out the other side. I love your advice to trust the process and his care team. 😊

I’ll keep you posted!

Thank you for being here Lori ! 🙏

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Replies to "Good morning Lori! Again, I am so grateful for your reassuring guidance and suggestions. Makes me..."
Lori, Volunteer Mentor | @loribmt | Mar 27, 2024

Hi Mary, just wanted to check in to see how your husband did with round two of his chemo. From my experience, each time seemed to take a little bit longer to rebound with energy level. You mentioned this was another induction round. So he may have another round called consolidation which is a good way of ‘sweeping up’ any remaining cancer cells.
The challenging thing with AML is that some cells can become resistant to the chemo, they can mutate or even go dormant and hide out only to emerge months later. So that’s why the stem cell transplant is important. From my experience and understanding on how this works, is that with mutations, your husband’s immune system no longer recognizes these as cancer cells so they are allowed to proliferate. It is the hope that a new immune system from a donor will again recognize the cancer cells if they emerge and snuff them out. It’s amazing and it can work. ☺️
So tell him to hang in there! Things get better. Hugs.

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