@pacathy Mucoid impaction is the same as mucus plugging. It seems that we all have some degree of mucus plugging. My understanding of the disease process is that mucus plugging/mucoid impaction can lead to bronchiectasis. Airway clearance as you suggested cannot hurt and it can only help with the mucus plugging/mucoid impaction.

Regarding NAC, Mucinex, I've read research articles that show benefit, and research articles that show no benefit. My take: NAC, mucinex break apart the mucus in our lungs and seemingly make it easier to expel. In that breaking apart process does it leave behind some of the broken apart mucus (phlegm) leading to further mucus plugging? Without NAC Mucinex the phlegm globs remain in tact and in theory can be huffed out all in one piece. Still, I would like a pulmonologist with knowledge, training and experience to explain it all to me. Until then do what you feel works for you!