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DiscussionPancreatic Cancer Group: Introduce yourself and connect with others
Pancreatic Cancer | Last Active: 2 days ago | Replies (1435)Comment receiving replies
Replies to "I also have no first-hand knowledge, but I was curious since I'd never heard anything about..."
I was diagnosed with stage 4 pancreatic cancer in November 2023. Since I am 78 and have several comorbidities the oncologists I have talked to say that the chemo/radiation treatments would probably kill me before the pancan would. I have been eating broccoli sprouts that I purchase at a local store twice a day for about 6 weeks now. I have no nausea or vomiting but am considering using the capsules which would be easier. Just wanted to know if anyone else had tried it. I will continue to report back if anything negative occurs or if the cancer stops progressing which is what I was hoping for. I know it's unlikely but it's better than just waiting to die.
Yep, good link, as are most at MSKCC...
That page had 4 mentions of pancreatic cancer:
1) "Talk to your healthcare provider if you have advanced pancreatic cancer. Using high-dose broccoli sprout supplements while on chemotherapy can increase nausea (feeling of throwing up) and vomiting (throwing up)."
2) "In patients with prior melanoma, a broccoli sprout extract was found to be well tolerated (15). A feasibility study involving advanced pancreatic cancer patients found some benefits with broccoli sprout supplementation but noted difficulty in capsule intake by some participants, and to be associated with increased digestive symptoms (19)."
3) is a word-for-word repeat of #2.
4) Is the link to reference (19) in #2:
Lozanovski VJ, Polychronidis G, Gross W, et al. Broccoli sprout supplementation in patients with advanced pancreatic cancer is difficult despite positive effects-results from the POUDER pilot study. Invest New Drugs. 2020 Jun;38(3):776-784
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211206/
It's a long report, but a summary of its summary includes"
"Compared to those of the placebo group, the mean death rate was lower in the treatment group during the first 6 months after intake (day 30: 0%/18%, day 90: 0%/25%, and day 180: 25%/43%), and Kaplan-Meier analysis revealed a higher survival rate. There was a high drop-out rate (72% in the treatment group and 55% in the placebo group) after 1 year. We concluded from the Karnofsky index that the broccoli sprouts did not impact patient’s self-care and overall abilities severely. The intake of 15 capsules daily was difficult for some patients, and the broccoli sprouts sometimes increased digestive problems, nausea and emesis. We did not obtain statistically significant results (p = 0.291 for the endpoint at day 180), but the knowledge about the feasibility is the basis for the development of new sulforaphane drugs."