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Survival Rates By Cancer Stage

Prostate Cancer | Last Active: Mar 29 4:06pm | Replies (22)

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@wooldridgec

I would add it also depends on the type of prostate cancer you may have. For example, do you have BRAC1 or BRAC2, or some other genetic marking. Did you start with adenocarcinoma, small cell, basal cell, or neuroendocrine. Some doctors now believe that at the time you are diagnosed you have a mix of prostate cancer cell types. And that micro mutations of those cells can sit around and fester over time and then emerge later because those cells were resistant to treatment all along. This is why doctors now believe in hitting the cancer hard up front with triplet therapy. The idea is to kill as many micro metastases as possible. Cancer cells are kills with radiation and or chemotherapy. ADT and the 2nd generation drugs like Xtandi, Darolutamide, Apalutamide stop cancer cells at the cellular level. Both starve cancer cells of testosterone. But some of cells can go dormant and rise up later. The good news is that all cancer cells must die. They do not die on schedule but they do die. My strategy was kill as much cancer as possible up front - hopefully leaving nothing to come back. But everyone is different and can only handle what they can handle. Some people are afraid of radiation and chemo so they settle for just ADT or one of the other drugs. I wanted to carpet bomb the cancer. I wanted to kill as many cells without killing myself for the greatest outcome. It was hard but the Lord got me through it.

No doctor can tell you your expected outcome. Some cancer just give up and become indolent and others mutate into something more aggressive. They do not know. But, we have lots of treatment options to extend our lives Thank God.

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Replies to "I would add it also depends on the type of prostate cancer you may have. For..."

You got it right friend.
Just one thing to add. It makes a world of difference to have a doctor whose aim on the outset is to CURE, not control. Dont rely too much on these articles or videos without the help of your doctor or at least a friend who is a doctor. If nothing else, they only add to unnecessary anxiety, especially articles written for medical professionals.
Dont mind me. I am just another layman trying to make some sense of the whole thing.

I also like the idea of throwing the kitchen sink at it early on if you're dealing with locally advanced disease or worse. I had BCR after RP so have hit some nodes that showed mild uptake with 38 fractions of IG/EBRT followed by 2+ years of Orgovyx + abiraterone. My MOs weren't ready to pull the chemo lever for triplet therapy yet based on the results that were recently reporting out of one of the arms of the STAMPEDE trial for the treatment protocol I'm on. They're predicting 75% chance of no BCR at 10 years, which sounds optimistic to me but they're pulling it from one of the premiere clinical trial platforms out there. That would put me at 77 y/o. If I could get those years in relatively good health, put me down for it!