← Return to Evenity cardiac and stroke side effects update

Discussion

Evenity cardiac and stroke side effects update

Osteoporosis & Bone Health | Last Active: Mar 20, 2024 | Replies (26)
Comment receiving replies
@imay

I think that of the two studies that have been done, FRAME and ARCH, one showed a hightened risk of major acute cardiovascular events, and the other did not. The one that involved older subjects it the one that showed a risk.

Jump to this post

Replies to "I think that of the two studies that have been done, FRAME and ARCH, one showed..."
windyshores | @windyshores | Mar 16, 2024

@imay the one comparing Evenity and alendronate showed increased risk (not large, but reported) and the study speculates that it might be because alendronate is slightly protective.

The one comparing Evenity and placebo showed no difference in cardiovascular risk.

As I wrote before, I am more concerned with aspects of Evenity that need further study, such as bone marrow edema and lower B cell production.

VIEW AND REPLY