Be cautious about too much prednisone. I am now having a total hip replacement due to vascular necrosis. When I inquired about cause my orthopedic surgeon said only known case is prednisone! I had multiple infusions and took high prednisone doses to try to save my hearing - I had Ménière’s disease in both ears. I now have severe hearing loss and a vascular necrosis in both hips!