I did the full dose of Tymlos for one month, and then a half dose or less for the second month. Side effects were bad -- pulse rate over 100, and feeling bad for hours. Doing it at night just ruined my night's sleep.
I wish I had started with a very low dose of Tymlos, maybe 2 clicks out of 8, or 25%. Perhaps I could have developed a tolerance for it. Please note I weigh 92 pounds -- which may explain why the normal dose was too high for me.
My doctor checked my bone markers before and after 2 months (C-terminal telopeptide (CTX) for bone resorption, and procollagen type 1 N propeptide (P1NP) for bone formation, in blood tests), and they both went up a lot (multiplied by three or four times, really)! I think that means that even the low dose was having the desired effect.
I'm switching to Forteo, which may be mistake, because apparently it's not possible to adjust the dose of the injection pen. I'm disappointed! I'll start with alternate days, and pray my pulse doesn't race again.
BTW, I did a year of Evenity first, with very good results. My only side effect was a slight, chronic tingling in the toes of one foot. Since I'm thin, I got the 2 injections in the sides of my thighs, which worked well. My BMD improved by about 12%.