There are known and documented side-effects with all ADTs. Some are “possible” while others are “likely.” Always focus on the “likely” ones. Most men experience some of these side-effects of hormone therapy to varying degrees — some more, some less —> forgetfulness, confusion, memory loss, mood swings, emotions, fatigue, loss of libido, ED, insomnia, hot flashes, night sweats, muscle atrophy, weight gain, and more….

There are ways to minimize many of these side-effects. Here are videos from recent PCRI conferences about ADT and the physical benefits of exercise:

As for your arthritis…. Similarly, my bone scans, though they are negative for metastatic disease, show (what I could have easily told them) that I have “….degenerative changes in lower lumbar spine and multiple joints (shoulders, sternoclavicular joints, elbows, wrists, knees, ankles, feet, right humeral shaft….likely non-specific and represents a benign process).” Basically, my sports injuries from football, track, gymnastics, and more…..many decades ago have all come back to haunt me now in my 60s.

Still, I push through it because I have to; no excuses.