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Breast cancer treatment and osteoporosis

Breast Cancer | Last Active: Mar 20 8:29pm | Replies (70)
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@petal

That’s a really good question! I personally do not know anyone or have read any research on the percentage of people who DID NOT not get osteoporosis after 5 years of AI treatment. Especially for post menopausal women. I have a friend in her forties who who got Osteoporosis after 5 years on Tamoxifen. Asking Mayo Clinic, do you have any research or statistics? Thank you.

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Replies to "That’s a really good question! I personally do not know anyone or have read any research..."
Colleen Young, Connect Director | @colleenyoung | Mar 14 12:19pm

@petal, that's a very good question. Aromatase inhibitors are known to cause a loss of bone density, which can lead to osteoporosis and bone fractures. Studies may not show the numbers you are looking for. But you could search for rates of incidence per side effect. For example see this review:

Amir E, Seruga B, Niraula S, Carlsson L, Ocaña A. Toxicity of adjuvant endocrine therapy in postmenopausal breast cancer patients: a systematic review and meta-analysis. J Natl Cancer Inst. 103(17):1299-309, 2011. https://pubmed.ncbi.nlm.nih.gov/21743022/

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timely | @timely | Mar 15 11:07am

I have a friend on another BC site who is 80, exercises daily with weight bearing exercises, and takes D + K4 and was able to increase bone density.
Her oncologist was pleased.
She takes an AI but no osteoporosis meds.

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