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Sudden drop of BMD while on Prolia.

Osteoporosis & Bone Health | Last Active: Mar 25 4:33pm | Replies (32)

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@connectalant

I am a six year user of Prolia. My DexaScan recently showed a 10% drop in BMD over the past 2 years. Confirmed on a retest. Another scan at a very reputable clinic showed no decline over a 5 year period. I realize different machines produce different readings, but the BMD and T-scores are significantly different. With the 10% drop shown, I am now faced with a decision on a successor medication to Prolia. Tymlos or Forteo have been recommended, but I am concerned with the rebound effect of Prolia if I change to either of these drugs.

Any thoughts?

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Replies to "I am a six year user of Prolia. My DexaScan recently showed a 10% drop in..."

I have used the same machine for many years.

Sorry to keep adding the info, but the drop in BMD was only in my hip.

@connectalant I posted in another thread on how switching to Tymlos of Forteo if you have been on Prolia more than 1-2 years is not a good idea, based on Great Bones" by Keith McCormick (page 569) and the excellent YouTube by Dr. Ben Leder on Combining and Sequential Approaches to Osteoporosis (minute 35 as I remember). Not only is this switch not effective, according to them, but it can make things worse. These resources and my own doctors say that Reclast is the only med that can avoid the rebound, or possibly to a lesser extent, Fosamax. Or you could stay on Prolia for longer-?