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Anyone on Paclitaxel? Does it work better?

Esophageal Cancer | Last Active: Mar 13 10:55am | Replies (6)

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@mrgvw

Yes... treatments must be changed once the first line treatments are no longer showing progress. And progress can mean that existing cancer is being held in check... not going away, but also not growing more and spreading more (that is also considered a win). But expect more changes, to Capecitabine pills (Xeloda)... which is a different form of the 5FU he got in Folfox. Also, sometimes the Oxaliplatin is changed out in Folfox for Irinotecan, which now makes the Folfox into Folfiri. And then there is Cisplatin, Carboplatin, Taxotere, Epirubicin, etc. And they may combine these with different immunotherapies as well... even when the patient may not be Her2 positive or show high PDL1 expression.

But still, an uphill battle unless one of these regimens takes care of all spread, and the patient can become surgery eligible. This is rare, but does happen. We just need to see the patient's body and cancer respond to these treatments.

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Replies to "Yes... treatments must be changed once the first line treatments are no longer showing progress. And..."

Thank you. I hope it does. I hate to see him losing hope as he’s always had a very optimistic outlook.

First, I want to thank you and others how you share all the knowledge. The more research and knowledge when talking and able to ask questions to the doctor the better you are.
In my husband's case, doctor already said it will be almost a miracle if he will be eligible for surgery. We have to be realistic and live with keeping the cancer cells not spreading out of control is a great situation.
Even thought the tumor or lesions are diminish to the point that testing doesn't pick up, he will always have cancer cell in his bloodstream and could pop out anywhere unfortunately.