I discovered today that Sonic Laboratories (one of Australia's largest pathology labs) can reliably screen for genetic markers to inform response to Leflunomide. Here the test is not covered by our Medicare insurance and costs $197. This is the next drug my Rheumatologist wants to try if Mtx is not successful. The laboratory does not test for response to Methotrexate, Prednisone or Tocilizimab. I will happily pay for this test before submitting to more 'trial and error ' drugs that could have dire consequences. I agree, the situation for PMR sufferers is quite dire and i wonder if there any organizations lobbying for clinical trials and better access to safer and more effective treatments.