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Conflicted/Confused, any Guidance/Advice out there?

Prostate Cancer | Last Active: Mar 31 2:33pm | Replies (72)

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@ranger44

I am 70 years old ( as of October 23) my PSA had gone from 4.24 to 6.62 in 6 months so my urologist ordered a Parametric MRI and a 4K score blood test, MRI showed a 12mm lesion on the right side mid gland and came back Pirads 4, the 4K score was the maximum at 95% of clinically significant cancer. Sure enough the MRI Fusion perineal biopsy at Mayo Phoenix show 9 of 23 cores cancer, with 6 at 70% 4+3=7 and 3 cores 40% 3+4= 7 and 14 cores benign. I had the PSMA PET which confirmed the tumor on the right, but no other spread outside the prostate. I then had the Decipher test and it came back low risk at 0.38. I looked into surgery and met the Mayo surgeon, who said at my age and weight ( 250 lbs) I was not a good candidate for surgery and he reiterated that it was major surgery with serious life changing side effects and possible major complications. After learning all the details of the surgery, there is no way I would even consider it. My prostate was 50.4 cc about the size of a lemon, they cut the whole thing out and to make up the missing 2+ inches of the urethra they pull the bladder neck down and the urethra up shortening your penis 1-1.5 inches, the cancer returns in about 20 - 30% of surgeries and you need further treatment like radiation or God forbid ADT and hormones. Radiation also has serious side effects and Erectile Dysfunction in 20-40% of cases, plus possible bowel problems. I then looked into Focal Therapy, talked with my Mayo Urologist yesterday, was really depressed that even the focal therapies like Hifu have side effects, ED in 20% of cases, possible rectal fistula, urine leaking into the bowel and you need surgery and have to wear a bag, also you have to have a Foley catheter for 1-2 weeks. I am looking into the Tulsa Pro which they do in Rochester , not in Phoenix. Considering my relatively low PSA at 6.62, Low Risk Decipher score of 0.38, tumor grade T1c and small volume tumor less than 1cc or 2% of prostate volume, I am considering Active Surveillance, at 70 my PCa may never metastasize in the next 10 years and I would more than likely die from some other cause. The ProtecT study in the UK shows no difference in mortality with Intermedate Risk patients over 15 years . 1/3 had surgery, 1/3 had radiation and 1/3 Active surveillance. Quality of life is much more important to me than quantity, and in my own personal opinion, if I had the choice to either wear diapers the rest of my life, have ED and possible bowel problems, or be dead, I would rather be dead. I am now leaning toward no treatment of any kind ever, just metobolic therapy and Ketogenic diet to starve the cancer cells of Glucose, I does extensive research on this watched Dr. Thomas Seyfried you tube videos, also Dr Ken Bary and many others. While I understand that many with PCa are always talking about treatments on this support group, I have yet to see someone with4+3=7 talk about no medical treatment. If I had 3+3 or 3+4 I would definitely not have treatment of any kind

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Replies to "I am 70 years old ( as of October 23) my PSA had gone from 4.24..."

Has your urologist mentioned a plant-based diet? Studies are beginning to show a slowing of prostate cancer progression in patients who adopt a whole-foods, plant-based diet. Small studies but intriguing and encouraging.

Thank you for the response and great information. The side effects of surgery or radiation for those who experience them are pretty tough on a guy. I wish you the best of luck and agree with your choice regarding your situation.

@ranger44
From reading your post it sounds like you have decided what is best for you and that is exactly what you should do. It can be difficult to deal with all the type treatments and side affects that are there with RP and radiation therapy.

If quality of life not quantity is your prime goal then you are answering your own discussion. It is you that must decide what is best for you and what you want out of life. I had the same Decipher test result of Low Risk. This means the risk of metassising is low. If monitoring is what you feel is best for you then do so.

I chose proton radiation at a very experience facility who specializes it that treatment. I did have some side affects but were minor and corrected themselves over time. I did not have to take any medication or procedure done during or after treatments. Side affects are going to happen regardless of type radiation you get as you are damaging not only your prostate but the areas around prostrate even with SBRT and proton.

The biggest difference in photon and proton is that proton does NOT exit the body but stops at prostrate or the site area the oncologist/radiologist programs into computer controlling beam. RP surgery is like you said a major surgery. I comes with a lot of side affects and long recovery. However some younger men with decades of life ahead choose the RP and many have said for peace of mind. I read some have good outcomes and some do not. But that is with any surgery.

Good luck!