← Return to Estradiol for vaginal atrophy after breast cancer. Is it safe?

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Hey there!
I’m a breast cancer survivor ( estrogen receptive) of 18 years. I also have severe atrophy . I Did chemo, radiation, 5 years of Tamoxifen snd 2 years of Famara.
I tried everything OTC, nothing worked for me. The Estradiol is the only med to give me relief. I’ve been using this cream for 15 years with no issues.
I use a 1/2 gram once every two weeks.
Every 6 months I go for labs to check that the level of estrogen in my body is well below my doctor’s expectation.
All the best🙏🏻

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Replies to "Hey there! I’m a breast cancer survivor ( estrogen receptive) of 18 years. I also have..."

Thank you for that info! That does make me feel better. Did you start off with more at first? My gyno wants me to start with once a day for a week. Then go down to once a week. You saying once every two weeks sounds good.

Kensiejames: I am just looking at your March 2024 comment in July 2025. Your specifics are SO HELPFUL. And relieving. I am 3 years after estrogen receptor+ breast cancer/chemo/radiation and am on Letrozole. (And I'm in my late '70's.) I read about estrogen cream for the vaginal dryness that keeps me from intercourse with my husband, and queried my oncologist via my electronic chart. She didn't reply personally, her RN did. She said they thought it was safe and offered to phone in a prescription for me. That's it. There are some women's doctors who are good at their specialty but really don't know how it feels to have cancer, and don't appreciate how much we REALLY DON'T WANT TO HAVE IT AGAIN. So anything that has "estrogen" in the name that we're thinking of trying feels scary unless we have reassurance from a professional that it really is safe. So--thank goodness for this site, and a breast cancer site on Reddit for helping us all have more peace of mind. Thank you, Kensiejames.