The doses I use are as follows (daily): B12 500 mcg (micrograms), alpha lipoic acid 600 mg (as used in almost all studies), vitamin D3 5000 IU (but this one I use every other day), methyfolate (the preferred form of folic acid) 1000 mcg (probably safe up to 2000 mcg per day but opinions vary on this). Hope this helps. I use the powder form of alpha lipoic acid and mix it into juice. A third party tested and approved brand in the powder form is the Bulk Supplements brand (with which I have no connection, financial or otherwise).