I had my first Prolia shot in January and still am suffering bad side effects-bones cracking, gums inflamed, hair loss, bloated, and fatigued. I resisted the Prolia however several Drs. highly advised it. My osteoporosis is not horrible - I do vigorous exercise about 10 hours a week- weight training, barre, yoga, spinning and take a great amount of natural calcium from foods and supplements. I am 75 with a 55 year old body and Prolia has made me miserable. Mentioned this to my endocrinologist - and she will put me on actonel after 5 months of Prolia. I just want to go natural after all this but I heard I cannot go cold turkey from Prolia otherwise high risk of fracture. Really horrible to be held hostage by this drug. I had endometrial cancer 7 years ago and had chemo and internal radiation- I think the chemo weakened my bones.