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How long do the side effects of Lupron/Eligard last?

Prostate Cancer | Last Active: Mar 22 9:35am | Replies (26)

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@socoldad

Thank you all for sharing your experiences. I'm hoping for short term side effects. Original PSA was 15 and had undergone a prostectomy 18 months ago, PSA was undetectable until now. It had risen to (0.4). Thankfully my PET scan came back clear for mestasis. Going through beam radiation therapy (6 days in of 38 treatments). Doc recommended 1 shot of Lupron (supposedly lasts 3 months). I'm not looking forward to side effects of either treatment.

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Replies to "Thank you all for sharing your experiences. I'm hoping for short term side effects. Original PSA..."

My Salvage Tx was IMRT radiation 37 txs together with 4 mos ADT. I took Orgovyx.
Side effects (SEs) for me were moderate but manageable.
Difficult to differentiate between causes.
Radiation Proctitis was a SE for me, and it cleared 2 - 4 wks post radiation.
ADT caused fatigue, minor hot flushes, mental fog. I describe it as all the issues of a 73 yr old exacerbated.
All SEs abated substantially about 4 mos after ADT completed, except some residual mid afternoon fatigue, when my recliner looks particularly inviting.
Not an expert, but I think that Lupron comes in 1, 3 & 6 mos injections.
SPPORT trial supports 4 - 6 month short term ADT together with radiation to whole pelvic region (WPRT).
Good news is that my 2 PSA tests following salvage tx have been undetectable.
Short answer to the Q initially posted: Too long!
Good luck with your treatments.

@socoldad, just thought I'd check in. How are you doing? How is treatment going?