I am 66 year old with prostate “infections” at least 5 since I was 27 years of age. I have learned so much about the prostate and these damn PSA levels. So many things can cause a rise in that level anything from enlarged prostate, chronic prostate infections, infections and of course yes, cancer. Due to my Family History of prostate cancer, i.e. my Dad, his brother and my brother my Urologist pushed for me to have the biopsy which I finally did after putting it off for 4 months. Prior to that he did 4 procedures involving prostate, bladder and obtaining urine samples after prostate massage. I did some reading and ALL of those procedures could push the PSA up as they are stimulating and irritating the prostate. I had a negative MRI but I still agreed to the biopsy given my family history. I am awaiting results. The procedure went well. I had 2mg of Ativan in me which I took about 1.5 hours prior to the procedure and had no pain what so ever. Ativan is not for pain but I needed to have less anxiety and it did the trick. He did numb the prostate through the rectum with Xylocaine but I didn’t feel that either. I felt slight pressure from the “bites” of the biopsy tool but no pain. It was over before I knew it, hence the Ativan. Ask your Urologists if they will let you have Ativan or Valium or something similar, i.e. Benzodiazepines on board prior. Dont give up asking questions guys.