I am taking Mestinon. After 3+ years of suffering with shortness of breath, dizziness, Post Exertional Malaise, etc, I was diagnosed with POTS. The diagnosis was made as a result of a tilt table test. I take 1/2 tablet of Pyridostigmine (generic Mestinon) twice a day. My neurologist says that I will be taking it for the rest of my life. I have very few side effects. I got my life back and am now walking vigorously, playing golf, participating in aerobic dancing, etc. Once in awhile, after an especially busy day, I feel the need to take a break - get short of breath, dizzy, etc. My doctor says I still need to listen to my body. I continue to suffer with migraine headaches, but not everyday, and GI problems are present. I have had migraines on and off since adolescence. I, too, researched the drug and understand that it helps with acetylcholine transmission between nerves. In any case, I call it my wonder drug. Before I met my neurologist and received a fresh look at my Long Covid, I had settled into thinking that I would always be a less active person than before Covid. Good luck and if you try Mestinon, let me know how it goes.