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PMR Flair up From a Virus?

Polymyalgia Rheumatica (PMR) | Last Active: Mar 8 7:06pm | Replies (52)

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@cazwell50

Yes, I read that PMR has the highest rate in Norway and other parts of Scandinavia so that points to a genetic susceptibility. I then did a DNA test with ancestry.com and found that I have Norwegian, Danish and Swedish DNA. Not the majority but they also do a chromosome painter that shows where each origin sits. I can’t yet decipher the chromosome map but given I have 17% of my DNA from Scandinavia and the fact my mother had PMR too, makes me think that all I needed was a trigger. I still don’t know if it was vaccinations - I had the Zoster, COVID booster and flu - in the previous two weeks. I rarely get sick so I have a strong immune system already and the vaccines could have tipped me over the top. When I was a child my mother got tuberculosis and each year they did a Mantoux test on me. The idea was to get a positive reaction. After three years I didn’t and they said it was likely I would never get TB yet my father and brother Had positive responses. I react quite alarmingly to bites from insects. Sorry for the rave but I’m trying to understand immune responses - environmental and genetic. I hope my daughter doesn’t get this as she has inherited the 5% Norwegian but none of the other DNA, which came from my fathers side. FYI photo of part of the story

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Replies to "Yes, I read that PMR has the highest rate in Norway and other parts of Scandinavia..."

2020, I had a PMR Dx, my grandmother (100% Swedish) had symptoms of PMR, although no diagnosis as far as I know.

I am 51% Swedish in genetic studies and I followed the profile of onset being at 70 years of age, w/o any other joint issues before the onset of PMR. My diagnosis came after a very stressful event.

Best of luck to all and keep researching for the best care. When I was at my worst this website gave me hope and leadership, it had a positive influence on my recovery.