Connect
← Return to Undecided choice of drugs for Osteoporosis
Discussion
Undecided choice of drugs for Osteoporosis
Osteoporosis & Bone Health | Last Active: Sep 8 8:12am | Replies (393)Comment receiving replies
Mannstadt must have an opinion about extended Forteo, even if he'd be reluctant to prescribe it that way. He likely knows the most about mineral metabolism with pth. What about a one time reclast infusion while remaining on Forteo. Janflute, you are giving me ideas.
What will he have you do after the reclast?
Replies to "Mannstadt must have an opinion about extended Forteo, even if he'd be reluctant to prescribe it..."
Adding a bisphosphonate to forteo may not be a good idea. Years ago, a small study used alendronate with forteo, results were worse than forteo alone. Considering Reclast is a lot stronger than allendronate, adding it to forteo may further dampen forteo’s effect.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853981/
It’s intersting that prolia combined with forteo has a better outcome than forteo alone as Leder etc. demonstrated.
He had said just one Reclast infusion when I started Forteo in July,2022. I was 75 at that time.
Connect
Doc will probably use monitoring after a Reclast infusion to determine if and when drug holidays can happen, from what I gather. MGH does not seem to do CTX and P1NP so I am curious what monitoring entails.