I did drop a little on the Acterma, a couple months of alternate weeks instead of weekly, but that was to see if my infection would rise back up as opposed to withdrawal. As far as Prednsone, taper off as low as you can reasonable go for as long as you can. My first rheumatologist had me stop that abruptly at around 10mg. Had withdrawal like you see dope addicts in movies. Dry heaves, severe vomiting. I had to go back on 20mg and taper off again at MY speed down to about 1/2 mg every other day.