@ykr I have only been on Tymlos for 3.5 months but I only inject in my lower abdomen. My understanding is that it’s not to be injected into muscle. You should check with your doctor or contact the Tymlos clinical educator network for the best advice on where to inject.

The thigh is a subcutaneous site as well as an intramuscular site. The difference is in how you do the injection and where on the thigh the injection is administered. Tymlos is definitely only subcutaneous. Thanks for your input and take care. YKR

I've been getting bruising at the injection site on my belly..ideas why?

@maradeur I have also been getting bruises from giving injections in my belly. I think it's because I'm thin and don't have much fat there. Others have suggested the thigh. My endo said that I can inject into the outside of my thigh if I want.

I have adequate belly fat. No problem for 6 months...

Does anyone get side effects from the Tymlos ? I just started on it and have had terrible headaches . Do they go away?

@franie, I started on Tymlos in June of 2023 and, like you, the headache was horrible. So, I decreased my dose for several months before working back up to full dose. I still get a headache soon after the injection but it only lasts about an hour. I found that if I take xtra strength Tylenol just before the injection it helps with the headache. Good luck to you!

I had horrible side effects from the full dose of Tymlos, a bad headache, dizziness, light headedness and nausea. As suggested by @windyshores, I cut back to 2 clicks or 20 mcg. I have slowly worked up to 4 clicks or 40 mcg which is a half a dose. I am tolerating this after a week. My endo believes that it doesn't matter how much you take. It works by kicking up the amount of parathyroid hormone briefly.

Hello @ykr, I combined your discussion with another discussion of the same title, https://connect.mayoclinic.org/discussion/tymlos-injection-sites.

@karenw9 started the discussion wondering about Tymlos injection sites as well and may appreciate seeing some of the other responses you received from @jmla, @maradeur and @drsuefowler.