I was found to have an invasive lobular carcinoma in left breast last August. Had mastectomy to remove large tumor and 29 lymph nodes. Scan following was clear of cancer. I am post menopausal at 86 years old, but quite active and healthy. Over the past decade I have been diagnosed with osteopenia and have taken raloxifene to prevent further deterioration. It worked. Now with my post-mastectomy prescription of letrozole inhibiting what estrazone was still in there protecting bones and no more raloxifene allowed, doctor is giving me Zometa infusions every 6 months to stave off any further bone loss. I also have completed 29 radiation treatments. I could not tolerate pill Verzenio, the third treatment recommended. No chemo. Doc will find something else for that, I guess. Seems to be a good tested plan to me. So my thinking is yes, for goodness sake, if you are on estrogen blockers of any kind, get the infusions. Osteoporosis is nothing to shrug off! Best wishes to all of us, doing the best we can with our new little misbehaving cancer cells!!