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Support For Those Quitting Prolia

Osteoporosis & Bone Health | Last Active: Oct 2 7:15am | Replies (136)

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@windyshores

@michaellavacot did you ever consider Tymlos or Forteo? I had a 20% gain in spine with Tymlos. I am doing a few Evenity's and on to Reclast.

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Replies to "@michaellavacot did you ever consider Tymlos or Forteo? I had a 20% gain in spine with..."

Yeah, I considered them. The reason I did not choose those after Evenity was due to my hypercalciuria and also some genetic variants I have. Tymlos and Forteo are PTH analogs and can increase urine calcium. I already have high urine calcium so I figured they too would have reduced efficacy like I had with Evenity, or even worse. Also, I believe I have some genetic variants in the Wnt signaling pathway that could reduce the effect on these types of drugs. So then I was left with Prolia as my only option. I'm being really careful with taking my calcium every day because with Prolia, my body will not be able to take calcium as readily from my bones and if I don't get calcium every day, my blood levels with drop (hypocalcemia) and that's when everything goes sideways. I know the FDA just implemented a black box warning on Prolia for hypocalcemia for kidney patients as well.