Kidney problems while taking Tymlos

Posted by bec39 @bec39, Feb 25 5:17pm

Has anyone had kidney issues while taking Tymlos? I was diagnosed with mild Pelviectasis of both kidneys after three months on Tymlos, though I do have a history of kidney stones. I asked my PCP to test both blood and urine for high calcium and urine came back high therefore she ordered a Renal Bilateral Ultrasound. I understand from this wonderful forum that high calcium in both blood/urine can be serious, so I don’t understand why I got such pushback from my Dr. about testing.

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@bec39

I get your logic to try a full dose first and adjust based on how it goes…I wish I could do that but these drugs scare me!
I need to figure out my path after Tymlos, which will be here before you know it. Thanks for giving me the confidence to plead my case, you’re a great inspiration.

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bec39, ramping is the perfect way to let your body adjust and to reduce the scariness of these injections. I agree with your assessment of windyshores, and agree with windyshores on almost everything else. If you tell your doctor that you've been ramping afterward, you likely won't get the same response she received from her (unusually sweet) doctor. Confessions of this type can make doctors mad "Non-compliant" can appear on your chart in perpetuity. (Hasn't happened to me.)
Praying Tymlos works for you.

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@gently

bec39, ramping is the perfect way to let your body adjust and to reduce the scariness of these injections. I agree with your assessment of windyshores, and agree with windyshores on almost everything else. If you tell your doctor that you've been ramping afterward, you likely won't get the same response she received from her (unusually sweet) doctor. Confessions of this type can make doctors mad "Non-compliant" can appear on your chart in perpetuity. (Hasn't happened to me.)
Praying Tymlos works for you.

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@gently I once read that true compliance is telling your doc what you are doing!

I think it is different if you tell your doctor you are on two clicks vs telling your doctor that you could not tolerate 8 clicks but managed to work your way up to 6 (which is therapeutic). Key though is trying the prescribed dose first, or at least half of it.

My doc not only supports ramping up but based on my finally getting on a medication after years of trying, now suggests it to patients having similar problems. If I hadn't told him what I was doing, he might not have changed his practice in this way.

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Sure you read that, windyshores, after you wrote it down.
Your doctor is happily different.
We'll never know how many osteoporosis patients you've helped in your physician's office, on this site and on other sites as your reputation spreads like an offshore wind.
I was curious about the 6 click therapeutic comment. Is there medical literature. It would be my unqualified opinion that even one click would be somewhat therapeutic.
You are such a blessing

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@gently

Sure you read that, windyshores, after you wrote it down.
Your doctor is happily different.
We'll never know how many osteoporosis patients you've helped in your physician's office, on this site and on other sites as your reputation spreads like an offshore wind.
I was curious about the 6 click therapeutic comment. Is there medical literature. It would be my unqualified opinion that even one click would be somewhat therapeutic.
You are such a blessing

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@gently you are so helpful too. My doc was most happy with 6 clicks. I"ll ask him but I think he was even okay with 4. But a lot happier with 6 or 7!

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@gently

bec39, ramping is the perfect way to let your body adjust and to reduce the scariness of these injections. I agree with your assessment of windyshores, and agree with windyshores on almost everything else. If you tell your doctor that you've been ramping afterward, you likely won't get the same response she received from her (unusually sweet) doctor. Confessions of this type can make doctors mad "Non-compliant" can appear on your chart in perpetuity. (Hasn't happened to me.)
Praying Tymlos works for you.

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@gently, I’m new to Mayo Clinic Connect and I can’t imagine navigating through osteoporosis without it. Specifically - windyshores is the reason I was able to start Tymlos without so much anxiety, even though I did not start with a full dose but at 2 clicks. My PCP was against it at first as “all my other patients are fine with full dose”. I think she was not aware this was even possible, so now she does and maybe other patients will benefit. We have “butt heads” on other issues in the past and guessing there are notes in my chart that I’m a “difficult” patient….but we have to be our own advocate. I thank you for all your comments and support, I know I can’t get through this alone.

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I agree that @ windy shores has helped me tremendously. I am so very sensitive to everything. I tried the full Tymlos dose last Spring with horrible side effects. This fall I started with 20 mcg and have slowly increased to 40 mcg. My endo was OK with only 20mcg and thought that could be enough. However, while on that amount, I developed a stress fracture in my foot from just going on a walk. That's when I decided to slowly push up the dosage. Without Wendy's suggestion, I would not be able to take Tymlos at all.

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