mas0415 I know this will sound crazy - but a couple of years ago I had a hysterectomy and it cleared up my IBS-D as well as eliminated the massive hip girdle pain that my rheumatologist attributed to PMR and did not believe me that it was not the classic pain of PMR. It was first identified thru an MRI taken in the ER when my pain compelled me to go in. A vaginal sonagram confirmed the existence of several tumors that needed to be removed ASAP. Fortunately, they were all benign and so recovery is what I focused on. I have reduced many of my autoimmune problems as a result as well as completely eliminated the IBS-D. If you have any abdominal pain or other abdominal symptoms like bloating or tenderness I would suggest you visit your Gynecologist and don't take No as an answer until they order an MRI. My tumors were initially seen in a 2015 MRI but no one told me that it needed to be watched, and my doctor left the practice, so it fell thru the cracks. You need to make sure and read all imaging reports and ask questions - lesson learned.