Hi Lisa,

Alectinib and my body are not friends at the moment. I was on 1200 daily total and after 2 weeks I was having debilitating muscle pain & spasms- Muscles I didn't even know existed. It was so strange how it moved around from muscle to muscle. I am off alectinib for 2 weeks. I checked in with my doc this past Monday. Today is the 3rd-day alectinib free and I can touch my toes without crying out in pain. He will do labs every Friday - my CK level was 860 and my liver labs did not look good. My doc said we may try again with a lower dose in 2 weeks. Thanks for checking in, I was planning on going back to work part-time, but the date keeps getting pushed back. I need my work insurance to get care. How are you feeling? Was your latest scan okay? Are you on 1200mg a day? I also had a weird taste, mine was more of a soapy taste in my mouth not sour. But it disappeared after a few bites of the food- or a few sips of the drink. I was constipated while on alectinib. Even with massive amounts of fiber and laxatives, it didn't help much. Alectinib is a miracle for most stage 4 cancer patients- I will see how I respond with the lower dosage. I appreciate your feedback and supportive comments.