Yes, that is a high dosage and I am sure you are feeling those effects strongly. My husband started on 60mg and felt very "uncomfortable" (to put it mildly). His largest issue was with sleeping, he found that exercising in the evening and having a good wind-down period before bed helped a little bit. They took him off the prednisone once they determined that he was end-stage and there was no way his kidneys could get worse before his transplant. There was essentially no reason to check the IgA as the damage was done. The 5mg he is on now is super manageable for him. His sister ended up being a perfect match so she gave the beautiful gift of her spare to him and he is doing fantastic! Everyone is different of course, but I am sure you will be on prednisone post-transplant to manage the IgA. As I stated, we just celebrated his one-year kidneyversary and there have been no rejection signs and no signs that the IgA has done damage to the new kidney. I wish the best for you on this journey and please feel free to reach out if you have any more thoughts or questions. I wish you the best!