That drop is too steep. Try not to go more than 10% at a time. At 10mg, I was okay dropping by .5mg every 10-11 days (changeover is on Sunday or Wednesday). However, that didn't work for me after I hit 5mg, Arm pain reappeared and was increasing - after ten days at 4.5 I was noticeably uncomfortable. When I started 4mg, the pain worsened. Although I have osteoporosis and would REALLY like to get off prednisone as soon as possible, after three days at 4mg. I decided to backtrack. Took one 5mg tablet, then restarted at 4.75. Pain stopped, although I wouldn't go so far as to say that my arms feel exactly as they did before PMR... but then, I'm 80. Caveat is that I'm at 4mg now, so I can't report on how the whole distance will go. With each drop of .25mg, there has been no pain other than barely noticeable discomfort getting dressed in the morning. I don't think about PMR very often.

Also, I was told to avoid Advil and aspirin (NSAIDs). Tylenol is okay.