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What's your experience with Orgovyx (relugolix)?

Prostate Cancer | Last Active: May 16 10:19am | Replies (135)

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@michaelcharles

Orgovyx: I have some good news and thought that I would share it.

Salvage Radiation tx together with 4 mos ADT Orgovyx Feb - June 2023.

Following RP Aug 2022 w/ immediate 90 day postop BCR of .19.

Nov 2023: uPSA test undetectable at < .02 and Testosterone 274 (up from undetectable in Mar < 2.5 w/ Orgovyx)

Feb 2024: uPSA test continues undetectable at < .02 and Testosterone 347 (80% of pretreatment tx level).

Extremely pleased; and hoping for continued remission of my G 9 PCa w/ Extraprostatic Extension.

Orgovyx experience was "as advertised": Rapid reduction of PSA and Testosterone upon starting.

Dissipation of ADT SEs 95% (mild to moderate for me; still sucked) 4 - 8 mos after stopping.

We go from PSA test to PSA test, and my PCa is anticipated to raise its ugly head again at some point, but hoping/praying for extended remission and next generation treatments.

Best to all.

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Replies to "Orgovyx: I have some good news and thought that I would share it. Salvage Radiation tx..."

That's great news!
I just want to confirm, having Gleason 9 PCa w/ Extraprostatic Extension, your med team only prescribed 4 mos of Orgovyx?

If that's true it seems the docs are all over the chart on ADT use.

Mine was Gleason7 w/o Extraprostatic Extension and the doc is saying two years and now starting to chirp about staying on it with a steady PSA of < .006 for over a year now.

He's not even testing my t level. I may start insisting on the next blood test.

I wish you continued success!